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Abstract #4333

Enhanced Ellipsoid Mapping of Diffusion Tensor Breast MRI for Improved Lesion Conspicuity

Myra Shapiro-Feinberg1, Edna Furma-Haran2, Dov Grobgeld3, and Hadassa Degani4

1Meir Medical Center, Kfar Saba, Israel, 2Weizmann Institute of Sience, rehovot, Israel, 3Weizmann Institute of Science, Rehovot, Israel, 4Biological Regulation, Weizmann Institute of Science, Rehovot, Israel

Ellipsoid mapping of the breast with a specific colorization mode has been developed as a visualization means for evaluating the entire information embedded in breast Diffusion Tensor Imaging (DTI) and improve breast cancer detection. The 3D ellipsoid maps were displayed at voxel resolution with their shape and orientation determined by a respective eigenvalue-eigenvector pair of the associated diffusion tensor, followed by colorizing the ellipsoids according to the values of each diffusion tensor parameter. The results show that the enhanced ellipsoid mapping with λ1 colorization accentuating breast malignancy, may allow efficient differentiation of breast malignancy from normal breast tissue.

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