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Abstract #4354

A Comparison of Hyperpolarized Helium-3 and Xenon-129 MR Fractional Ventilation Imaging

Hooman Hamedani1, Kai Ruppert1, Yi Xin1, Stephen Kadlecek1, Faraz Amzajerdian1, Ryan Baron1, Ian Duncan1, Luis Loza1, Mehrdad Pourfathi1, Sarmad Siddiqui1, Harrilla Profka1, Mary Spencer1, Tahmina Achekzai1, Maurizio Cereda2, and Rahim R. Rizi1

1Radiology, University of Pennsylvania, Philadelphia, PA, United States, 2Anesthesiology and Critical Care, University of Pennsylvania, Philadelphia, PA, United States

In response to the global shortage of 3He, we studied the feasibility and safety of performing a multi-breath wash-in MR imaging technique to measure fractional ventilation using hyperpolarized (HP) 129Xe in the same manner as with 3He.

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