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Abstract #4380

Utility of Multiparametric Prostate Magnetic Resonance Imaging for Prediction of Treatment Response Following Focal Laser Ablation

Ely Felker1, Leonard Marks2, Fuad Elkhoury2, David S Lu3, Daniel Margolis4, Shyam Natarajan5, James Sayre6, and Steven Raman3

1UCLA, Los Angeles, CA, United States, 2Urology, UCLA, Los Angeles, CA, United States, 3Radiology, UCLA, Los Angeles, CA, United States, 4Radiology, Cornell, New York, NY, United States, 5Bioengineering, UCLA, Los Angeles, CA, United States, 6Biostatistics, UCLA, Los Angeles, CA, United States

We evaluated the utility of multiparametric prostate MRI, including T2-weighted imaging, diffusion-weighted imaging (DWI) and dynamic contrast-enhanced imaging, in predicting treatment response following focal laser ablation of prostate cancer in a multi-reader study. DWI appears to be the most useful sequence in response assessment, but inter-reader agreement was moderate at best.

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