Abstract #4380

Utility of Multiparametric Prostate Magnetic Resonance Imaging for Prediction of Treatment Response Following Focal Laser Ablation

Ely Felker¹, Leonard Marks², Fuad Elkhoury², David S Lu³, Daniel Margolis⁴, Shyam Natarajan⁵, James Sayre⁶, and Steven Raman³

¹UCLA, Los Angeles, CA, United States, ²Urology, UCLA, Los Angeles, CA, United States, ³Radiology, UCLA, Los Angeles, CA, United States, ⁴Radiology, Cornell, New York, NY, United States, ⁵Bioengineering, UCLA, Los Angeles, CA, United States, ⁶Biostatistics, UCLA, Los Angeles, CA, United States

We evaluated the utility of multiparametric prostate MRI, including T2-weighted imaging, diffusion-weighted imaging (DWI) and dynamic contrast-enhanced imaging, in predicting treatment response following focal laser ablation of prostate cancer in a multi-reader study. DWI appears to be the most useful sequence in response assessment, but inter-reader agreement was moderate at best.

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