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Abstract #4381

Preliminary Investigation of MR Elastography to Predict Lymph Node Metastasis in Prostate Cancer

Jin Wang1, TianHui Zhang1, Ying Deng1, Sichi Kuang1, Bingjun He1, Qungang Shan1, Jun Chen2, Phillip Rossman2, Arvin Arani2, Xin Gao3, Ziying Yin2, Meng Yin2, Kevin J. Glaser2, and Richard L. Ehman2

1Department of Radiology, the Third Affiliated Hospital of Sun Yat-sen University(SYSU), Guangzhou, China, 2Department of Radiology, Mayo Clinic, Rochester, MN, United States, 3Department of Urology, the Third Affiliated Hospital of Sun Yat-sen University(SYSU), Guangzhou, China

Prostate cancer(PCa) is one of the leading causes of cancer-related deaths in North American men. Nodal metastases occur in 3-42% of men with clinically localized prostate cancer and the presence of nodal metastases has a strong negative impact on survival. Lymph node staging plays an important role in planning initial management in nonmetastatic PCa. Early detection and resection are important for staging and for the prognosis. We evaluated the diagnostic performance of MR elastography (MRE) in patients with PCa. Results from 33 patients with PCa show that MRE at both of 60Hz and 90Hz has the potential to be a useful technique for predicting PCa lymph node metastases and to establish prognosis and treatment planning.

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