Abstract #4388

Diagnostic performance of qualitative and quantitative 3T DCE-MRI parameters of prostate cancer lesions in transition and peripheral zone stratified by pathology Gleason score and PI-RADSv2 score

Sohrab Afshari Mirak¹, Kyung Hyun Sung², Amirhossein Mohammadian Bajgiran¹, Nazanin Hajarol Asvadi¹, Ely R Felker¹, Preeti Ahuja¹, Anthony Sisk³, Robert Reiter⁴, and Steven Raman¹

¹Radiology, David Geffen school of Medicine at UCLA, LOS ANGELES, CA, United States, ²Radiological Sciences and Bioengineering, David Geffen school of Medicine at UCLA, LOS ANGELES, CA, United States, ³Pathology, David Geffen school of Medicine at UCLA, LOS ANGELES, CA, United States, ⁴Urology, David Geffen school of Medicine at UCLA, LOS ANGELES, CA, United States

We investigated the diagnostic performance of qualitative and quantitative parameters of dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) of prostate cancer (PCa) in 238 patients with 303 lesions located in transition (TZ) and peripheral zone (PZ) stratified by pathology Gleason score (GS) and PI-RADSv2 score with whole mount histopathology validation. There was a significant difference in qualitative and quantitative values between low and high-grade tumors and PI-RADSv2 scores in PZ PCa lesions. However, for tumors located in TZ, only DCE curve type was significantly different between low and high-grade PCa.

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