Recent consensus suggested breast MRI lacks necessary sensitivity or specificity to detect breast cancer. MRI may over-diagnose breast cancer and result in over-treatment. The novel diffusion MRI histology (D-Histo) method demonstrated its ability to accurately locate lesion and quantify cancer cellularity and afforded greater sensitivity and specificity than ADC did in distinguishing between tumor and benign tissues. D-Histo’s improved diagnostic accuracy thus better guides treatment planning, and more accurately measures treatment efficacy.
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