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Abstract #4448

The Value of DKI and IVIM Quantitative Parameters in Differentiating Breast Lesions and Correlations with Histopathologic Factors: A Preliminary Study

Chenglu Ke1, Shunan Che1, Jing Li1, and Lizhi Xie2

1National Cancer Center/Cancer Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China, 2GE healthcare, Beijing, China

The current study aimed to evaluate the application of diffusion kurtosis imaging (DKI) and intravoxel incoherent motion (IVIM) in the differential diagnosis of breast lesions. The association of DKI and IVIM derived parameters were compared with pathological types, histologic grade, and Ki-67 expression of primary breast cancers. The results indicated that MD, MK, D and f are capable of distinguishing benign from malignant breast lesions. Furthermore, significant correlations were observed between MD and different histologic grade and Ki-67 expression, repsectivley.

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