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Abstract #4454

Feasibility of multispectral spin echo breast quantitative susceptibility mapping: an alternative to post-biopsy mammogram after MR-guided breast biopsy

Sarah Eskreis-Winkler1, Katherine Simon1, Youngwook Kee1, Junghun Cho1, Thanh Nguyen1, Pascal Spincemaille1, Michele Drotman1, and Yi Wang1

1Weill Cornell Medicine, New York, NY, United States

During MR-guided breast biopsy, a titanium biopsy marker is deployed in the biopsy cavity to mark the spot. Conventional MR cannot distinguish between these markers and the pockets of air that are often introduced during the biopsy, necessitating a subsequent mammogram to confirm biopsy marker location. Our goal is to replace post-biopsy mammogram with a short MR protocol leveraging the difference in magnetic susceptibility between titanium and air in order to distinguish them as sources of MR signal voids. To this end, we generate quantitative susceptibility maps (QSM) using 3D fast spin echo acquired at four frequency offsets.

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