Meeting Banner
Abstract #4457

Addition of in-vivo proton MRS to DCEMRI increases the sensitivity of cancer detection in breast cancer patients especially in cases of indeterminate dynamic MRI findings.

Naranamangalam R Jagannathan1, Khusbhu Agarwal1, Uma Sharma1, Smriti Hari2, Vurthaluru Seenu3, Sandeep Mathur4, Siddhartha D Gupta4, and Rajinder Parshad3

1Department of NMR and MRI Facility, All India Institute of Medical Sciences, New Delhi, India, 2Department of Radiology, All India Institute of Medical Sciences, New Delhi, India, 3Department of Surgery, All India Institute of Medical Sciences, New Delhi, India, 4Department of Pathology, All India Institute of Medical Sciences, New Delhi, India

Potential of addition of in-vivo proton (1H) MRS to DCEMRI data especially in indeterminate DCE findings was evaluated. MRS and DCEMRI data of 56 breast cancer patients were included in the analysis. 47/56 cases showed type III curve indicating cancer with a sensitivity of 83.9%. MRS showed true positive findings of cancer in 44/47 cases. Among 9 indeterminate DCE cases, MRS was positive for cancer in 6 cases, implying that 50/56 cases were true positive for cancer with 89.3% sensitivity. Addition of MRS to DCEMRI data increases the sensitivity of cancer detection especially in indeterminate DCE findings.

This abstract and the presentation materials are available to members only; a login is required.

Join Here