Abstract #4459

Comparison of 1.0M Gadobutrol and 0.5M Gadoteridol for Kinetic Parameters on Breast Dynamic Contrast Enhanced Magnetic Resonance Imaging at 3T

Hajime Sagawa¹, Masako Kataoka¹, Shotaro Kanao², Natsuko Onishi³, Maya Honda², Dominik Nickel⁴, Masakazu Toi⁵, Katsuhiko Ueda¹, and Kaori Togashi²

¹Division of Clinical Radiology Service, Kyoto University Hospital, Kyoto, Japan, ²Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan, ³Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, United States, ⁴MR Application Predevelopment, Siemens Healthcare GmbH, Erlangen, Germany, ⁵Department of Breast Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan

The contrast effects of 1.0M gadobutrol were compared to that of 0.5M gadoteridol in breast cancer at 3T using hybrid MRI protocol which combined conventional DCE (C-DCE) with ultrafast DCE (UF-DCE). The significant differences were observed only in UF-DCE, maximum enhancement ratio (MER) and maximum slope (MS). The slightly higher peak relative enhancement produced by gadobutrol compared with gadoteridol might help in the detection and evaluation of breast lesions in the earlier phases.

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