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Abstract #4486

Restriction Spectrum Imaging-A Novel Diffusion-Based Technique for Detection and Characterization of Prostate Cancer

Ely R Felker1, Leonard Marks2, Fuad Elkhoury2, David Lu1, Daniel Margolis3, Sepideh Shakeri1, Pooria Khoshnoodi4, Lorna Herbert2, Nathan White5, David Karow6, and Steven Raman1

1Radiology, UCLA, Los Angeles, CA, United States, 2Urology, UCLA, Los Angeles, CA, United States, 3Radiology, Cornell, New York, NY, United States, 4Pathology, University of Minnesota, Minneapolis, MN, United States, 5UCSD, San Diego, CA, United States, 6Human Longevity Institute, San Diego, CA, United States

We evaluated the utility of restriction spectrum imaging (RSI), a novel diffusion-based technique to detect and to characterize prostate cancer among men enrolled in a national cancer institute-funded prospective clinical trial of magnetic resonance ultrasound fusion biopsy. RSI was statistically significantly associated with clinically significant prostate cancer.

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