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Abstract #4504

Histogram Analysis of monoexponential DWI, biexponential IVIM model and PI-RADS V2 for the Differentiation of Prostate Cancer from BPH in the Transition zone

jie bao1, ximing wang1, zhongshuai zhang2, su hu1, xiaoxia ping1, and chunhong hu1

1the First Affiliated Hospital of Soochow University, Suzhou, China, 2Siemens Healthcare Ltd., Shanghai, China


In this study, we propose to evaluate histogram analysis of ADC derived by traditional DWI model, diffusion related parameters calculated by using intravoxel incoherent motion (IVIM) model and PI-RADS V2 for the detection of the prostate cancer (PCa) in the transition zone (TZ). Our results show that the highest classification accuracy was achieved by the mean ADC (0.841) and mean D (0.809, acquired by the IVIM model). Our findings suggest that Monoexponential DWI and biexponential IVIM model could potentially improve the accuracy of the pathological grading of prostate cancer in TZ.

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