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Abstract #4546

Resting-state sensorimotor networks in adults with atypical swallowing: a fMRI study

Sidy Fall1, Stéphanie Dakpé2, Pauline Nicol3, Juliette Baudel3, Evane Pailler3, Sylvie Testelin2, Bernard Devauchelle2, Patrick Goudot3, and Jean-Marc Constans4

1BioFlow Image, University of Picardy, Amiens, France, 2Maxillo Facial Department, Facing Faces Institute, University Hospital, Amiens, France, 3Maxillo Facial Department, Pitié Salpétrière University Hospital, UPMC Paris 6, Paris, France, 4Radiology Department, Facing Faces Institute, University Hospital, Amiens, France

Most previous functional neuroimaging studies on swallowing were focused on investigating the cortical (and subcortical) representation of the swallowing functions in healthy individuals using task-related data. The present function magnetic resonance imaging (fMRI) study examine whether individuals with atypical and normal swallowing differ in brain activity patterns associated to the resting-state sensorimotor network. Our findings revealed that the individuals with normal swallowing showed stronger and broader patterns of activation than the individuals with atypical swallowing, particularly in the midcingulate cortex. These differences of activation patterns between the two groups may suggest that the midcingulate cortex is crucially involved in the coordination or/and integration of swallowing functions.

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