Abstract #4559

Assessment of the effect of maternal posture on the placental oxygenation transport by means of BOLD MRI

Esra Abaci Turk¹, Jie Luo^1,2, Natalie Copeland¹, Michelle Restrepo¹, Ata Turk³, Borjan Gagoski¹, Lawrence L. Wald^4,5,6, Elfar Adalsteinsson^6,7,8, Drucilla J. Roberts⁹, Polina Golland^7,10, P. Ellen Grant¹, and William H. Barth Jr¹¹

¹Fetal-Neonatal Neuroimaging & Developmental Science Center, Boston Children's Hospital, Boston, MA, United States, ²School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China, ³Electrical Computer Engineering Department, Boston University, Boston, MA, United States, ⁴Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States, ⁵Radiology, Harvard Medical School, Boston, MA, United States, ⁶Harvard-MIT Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, United States, ⁷Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, United States, ⁸Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, United States, ⁹Pathology, Massachusetts General Hospital, Boston, MA, United States, ¹⁰Computer Science and Artificial Intelligence Laboratory (CSAIL), Massachusetts Institute of Technology, Cambridge, MA, United States, ¹¹Maternal-Fetal Medicine, Obstetrics and Gynecology, Massachusetts General Hospital, Boston, MA, United States

Aorta-caval compression due to maternal posture can change uterine artery blood flow, which is the major determinant of maternal intervillous perfusion and may affect MRI measures of placental oxygenation. We investigated the effect of maternal posture on estimates obtained from BOLD MRI of the placenta. We observed higher oxygenation signals in the supine position for a group at younger gestational age. In the group with higher gestational age, the influence of the maternal position on oxygen transport was inconsistent. These findings underscore the need to account for the effect of maternal posture on MRI studies of utero-placental circulation.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.