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Abstract #4576

Metabolic imaging of rodent placenta using hyperpolarized 13C pyruvate MRI

Renuka Sriram1, Jeremy Gordon1, Robert A Bok1, Eugene Milshteyn1, Daniel B Vigneron1, Peder E.Z Larson1, John Kurhanewicz1, and Priyanka Jha1

1University of California, San Francisco, San Francisco, CA, United States

We have demonstrated the initial feasibility of hyperpolarized carbon-13 MRI assessment of placental metabolism in a pregnant rat model using [1-13C]pyruvate. This opens avenues for multiple applications investigating metabolic changes of placental dysfunction detrimental to maternal and fetal health.

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