Meeting Banner
Abstract #4577

Spatial Vascular Heterogeneity in the Normal Placenta Assessed with Multi-compartment Placental MRI

Rosalind Aughwane1, Andrew Melbourne1, David Owen1, Magdalena Sokolska2, Alan Bainbridge2, David Atkinson1, Jan Deprest1, Giles Kendall2, Tom Vercauteren1, Sebastien Ourselin1, and Anna David2

1University College London, London, United Kingdom, 2University College Hospital, London, United Kingdom

The placenta is perfused by the fetus and mother, allowing oxygen and nutrients to be transferred to the developing fetus. Histologically there is large variation in vascularity within normal placentae but this has not been studied in vivo. The DECIDE model was fitted to separate signals from fetal and maternal perfusion. We imaged placental perfusion using the multi-compartment MR DECIDE model over the placental volume to investigate signal heterogeneity in four uncomplicated singleton pregnancies. The spatial composition of the placenta is investigated by inspecting the parametric heterogeneity across the organ.

This abstract and the presentation materials are available to members only; a login is required.

Join Here