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Abstract #4601

T2WI Texture Analysis in Renal Cell Carcinoma: Histologic Subtype Classification

Zhenhao Liu1,2, Haiyi Wang2, Xu Bai2, Huiling Yi3, and Huiyi Ye2

1Affiliated Hospital of Changzhi Institute of Traditional Chinese Medicine, Changzhi, China, 2Chinese PLA General Hospital, Beijing, China, 3Qinhuangdao Municipal No.1 Hospital, Qinhuangdao, China

This retrospective study investigates the possibility of distinguishing between clear cell renal cell carcinoma ( ccRCC ) and non-clear cell renal cell carcinoma ( nccRCC ) using MRI-derived parameters by exploring a predictive method. We enrolled the patients with three common subtypes of renal tumor - clear cell renal cell carcinoma ( ccRCC ), papillary renal cell carcinoma ( pRCC ) and chromophobic renal cell carcinoma ( cRCC ). We combined pRCC and cRCC into one subtype - nccRCC. Our results demonstrated that MRI texture analysis can differentiate ccRCC from nccRCC with high specificity, sensitivity and accuracy and can probably facilitate the precise treatment of renal tumors in the future clinical practice.

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