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Abstract #4600

Assessment of Optimal Technique for Measurement of Medullary Perfusion

Chris R Bradley1,2, Charlotte E Buchanan1, Eleanor F Cox1,2, and Susan T Francis1,2

1Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, United Kingdom, 2NIHR Nottingham Biomedical Research Centre, University of Nottingham, Nottingham, United Kingdom

The ability to assess medullary perfusion is important in kidney disease, for example in acute kidney injury (AKI) in which reduced medullary blood flow is implicated. In this study, we compare the use of a spin echo (SE) EPI and balanced FFE (bFFE) readout at multiple post label delay (PLD) times to determine the optimal readout scheme and to assess the number of ASL pairs required to compute medullary perfusion. Using a bFFE FAIR ASL scheme, it is possible to quantify tissue perfusion within the renal medulla.

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