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Abstract #4604

Combined hepatocellular-cholangiocarcinoma: diagnostic and prognostic values of LI-RADS v2017 categorization on gadoxetic acid-enhanced MR imaging

Sun Kyung Jeon1, Ijin Joo1, Dong Ho Lee1, Sang Min Lee2, Hyo Jin Kang1, and Jeong Min Lee1

1Seoul National University Hospital, Seoul, Republic of Korea, 2Hallym University Sacred Heart Hospital, Anyang, Republic of Korea

Our retrospective study investigated the utility of Liver Imaging Reporting and Data System (LI-RADS) v2017 for combined hepatocellular cholangiocarcinoma (cHCC-CCs) in the differential diagnosis from HCCs and prediction of prognosis. Using LI-RADS on gadoxetic acid-enhanced MRI, among cHCC-CCs (n=70), 61.4% (43/70) were accurately categorized as LR-M (probable malignancy, not specific for HCC) while 37.1% (26/70) as LR-5/4 (definitely/probably HCC); among HCCs (n=70), 88.6% (62/70) and 10.0% (7/70) were categorized as LR-5/4 and LR-M, respectively. After surgical resection, patients with LR-M cHCC-CCs showed a higher early recurrence rate (≤6 months) than those with LR-5/4 cHCC-CCs (27.8% (10/36) vs. 4.8% (1/21), P=0.041).

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