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Abstract #4618

Comparison of Referenceless Methods for EPI Ghost Correction in Breast Diffusion Weighted Imaging

Jessica A McKay1, Steen Moeller2, Lei Zhang3, Edward J Auerbach2, Michael T Nelson2, and Patrick J Bolan2

1Biomedical Engineering, University of Minnesota, Minneapolis, MN, United States, 2Department of Radiology, University of Minnesota, Minneapolis, MN, United States, 3Clinical and Translational Science Institute, University of Minnesota, Minneapolis, MN, United States

Three-line navigator correction of Nyquist ghosts in spin-echo echo-planar imaging (SE-EPI) diffusion weighted imaging (DWI) often fails in body imaging. Several alternative strategies have been proposed including referenceless methods, which do not require any type of reference information but instead minimize a cost function based on the data itself. The purpose of this work is to assess ghost correction of undersampled (R=3) breast DWI using several referenceless methods, including minimization of SVD in k-space, image entropy, a ghost/object ratio of the image, and a combination. All four referenceless strategies outperform the standard navigator correction, providing higher quality images and unbiased ADC maps.

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