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Abstract #4619

Repeatability of Apparent Diffusion Coefficient measurements using Simultaneous Multi-slice Diffusion-Weighted imaging with elastic in-plane motion correction: a Comparison with Conventional DWI in Healthy Liver Parenchyma

Jia Xu1, Xuan Wang1, Tianyi Qian2, Shitian Wang1, Huadan Xue1, and Zhengyu Jin1

1Department of Radiology, Peking Union Medical College Hospital, Beijing, China, 2Siemens Healthcare, MR Collaboration NE Asia, Beijing, China

The simultaneous multi-slice (SMS) technique allows reducing the scan time of DWI without significant compromises in image quality. An adequate test-retest reliability of apparent diffusion coefficient (ADC) is essential for clinical use. The aim of this study was to prospectively compare the ADC value and test-retest repeatability of SMS-DWI with elastic in-plane motion correction in comparison to conventional DWI in healthy liver parenchyma. SMS-DWI and motion corrected SMS-DWI images (Moco-SMS) demonstrated significantly higher ADC values than conventional DWI in almost all liver regions. Moco-SMS showed significantly higher test-retest repeatability than conventional DWI in regions close to liver edges.

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