Abstract #4708

High-Resolution Intravoxel Incoherent Motion (IVIM) diffusion-weighted MR imaging for the characterization of periampullary lesions

Haixia Yu¹, Chuangliang Chen¹, Dapeng Shi¹, Robert Grimm², and Tianyi Qian³

¹Department of Radiology, People’s Hospital of Zhengzhou University, Henan Provincial People’s Hospital, Zhengzhou, China, ²MR Application Predevelopment, Siemens Healthcare, Erlangen, Germany, ³Siemens Healthcare, MR Collaborations NE Asia, Beijing, China

This study aimed to investigate the clinical diagnostic utility of ZOOMit-DWI-based IVIM imaging technology^[1,2] for periampullary lesions. Forty-one patients, comprising cancer of the pancreatic head (n = 6), chronic pancreatitis (n = 9), ampullary adenocarcinoma (n = 9), and distal bile duct carcinoma (n = 17) and 28 healthy volunteers were enrolled. Our results showed that the perfusion fraction (f) of the IVIM-derived parameter has the potential to distinguish between cancer of the pancreatic head, other lesions, and normal tissue in the periampullary regions by using the zoomed DW imaging, which has the capacity to overcome some of the limitations of conventional MRI of the pancreas.

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