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Abstract #4709

Evaluation of Extracellular Volume (ECV) Fraction of the Normal Pancreas and Correlation with Biophysical Parameters

Temel Tirkes1, Kumaresan Sandrasegaran1, Eugene P Ceppa1, and Chen Lin2

1Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, United States, 2Indiana University School of Medicine, Indianapolis, IN, United States

ECV fraction can be a very useful imaging tool for non-invasive evaluation of solid organ pathologies and is probably underutilized in abdominal imaging. There are potentially several clinical applications of ECV in the abdomen such as evaluation of chronic pancreatitis or chronic liver disease. In this study, we computed the ECV fraction of the pancreas in 60 healthy cohorts and determined that ECV fraction of the normal pancreas is 0.26 (± 0.08). ECV fraction is not influenced by pancreatic steatosis or patient’s gender, however gradually increases with age.

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