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Abstract #4722

Diffusion-Weighted MR Imaging of rectal cancer with A Fractional Order Calculus Model

Yanfen Cui1, Zhizheng Zhuo2, and Xiaotang Yang3

1Department of Radiology, Shanxi Province Tumor hospital, Taiyuan, China, 2MR Clinical Sciences, Philips Healthcare Greater China, Beijing, China, Beijing, China, 3Shanxi Province Tumor Hospital, Taiyuan, China

A novel non-Gaussian diffusion model based on fractional order calculus (FROC) were successfully applied to diffusion MRI of rectal cancer. Statistically significant differences in D and β values are observed between rectal cancer and villous adenoma (p < 0.001), indicating that individual or combined parameters from the FROC diffusion model may be useful as imaging biomarkers in predicting the biological properties of rectal cancer in clinical practice.

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