Abstract #4722

Diffusion-Weighted MR Imaging of rectal cancer with A Fractional Order Calculus Model

Yanfen Cui¹, Zhizheng Zhuo², and Xiaotang Yang³

¹Department of Radiology, Shanxi Province Tumor hospital, Taiyuan, China, ²MR Clinical Sciences, Philips Healthcare Greater China, Beijing, China, Beijing, China, ³Shanxi Province Tumor Hospital, Taiyuan, China

A novel non-Gaussian diffusion model based on fractional order calculus (FROC) were successfully applied to diffusion MRI of rectal cancer. Statistically significant differences in D and β values are observed between rectal cancer and villous adenoma (p < 0.001), indicating that individual or combined parameters from the FROC diffusion model may be useful as imaging biomarkers in predicting the biological properties of rectal cancer in clinical practice.

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