Abstract #4727

Validation of gadoxetate dynamic contrast-enhanced MRI to assess liver function in rats with liver fibrosis: comparison with shear wave elastography and indocyanine green test

Jimi Huh¹, Su Jung Ham², Young Chul Cho², Seul-I Lee², Jisuk Park², Chul Woong Woo², Yoonseok Choi³, Dong-Cheol Woo², and Kyung Won Kim²

¹Radiology, Ulsan University Hospital, Ulsan, Republic of Korea, ²Asan Medical Center, Seoul, Republic of Korea, ³Gangneng Asan Medical Center, Gangneng, Republic of Korea

Non-invasive imaging evaluation of the liver fibrosis and liver function has been gaining emphasis currently. In preclinical trial with animal liver fibrosis model, the gadoxetate DCE-MRI is quite feasible to evaluate histopathologic liver fibrosis and physiologic liver function in a non-invasive and repeatable manner. The best MRI index would be the iAUC-15, which is better than kPa on SWE.

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