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Abstract #4740

The preliminary study of staging liver fibrosis in patients with chronic hepatitis B using MR T1ρ

Qing Li1, Shuangshuang Xie1, Hanxiong Qi1, Zhizheng Zhuo2, Yue Cheng1, and Wen Shen1

1Radiology department, Tianjin First Center Hospital, Tianjin, China, 2Philips healthcare, Beijing China, Beijing, China

This study explored the value of MR T1ρ in patients with chronic hepatitis B. Twenty normal control subjects and forty-eight patients with chronic hepatitis B, including twenty-two patients who were confirmed by liver biopsy (F1/F2/F3=8/8/6) took the MR T1ρ scan. T1ρ value showed significant increase in patients with chronic hepatitis B compared with normal control subjects, significant correlation with liver fibrosis staging and higher sensitivity and specificity in identifying F1 to F3 of liver fibrosis. We conclude that MR T1ρ can provide reliable T1ρ values and can be used to assess liver fibrosis.

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