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Abstract #4747

Gd-EOB-DTPA-Enhanced MRI for Assessment of Liver Function: Comparison between Signal Intensity and T1 Relaxation Time-Based Indices

Xueqin ZHANG1, Jian LU1, Jifeng JIANG1, and Weibo CHEN2

1Department of Radiology, the Third People’s Hospital of Nantong, Nantong, China, 2Philips Healthcare Shanghai, Shanghai, China

The purpose of this study was to compare the ability of Gd-EOB-DTPA-enhanced signal intensity (SI) and T1 relaxation time-based indices for evaluation of liver function. We used Gd-EOB-DTPA-enhanced MRI and Look-Locker sequences to acquire conventional MRI and T1mapping images. The SI values of the liver, paravertebral muscle, T1 relaxation times of the liver before Gd-EOB-DTPA administration and in HBP were measured, the relative enhancement of the liver, increase rates of liver-to-muscle ratio, reduction rates of T1 relaxation time and ΔR1 were calculated, our study showed that the indices derived from T1 relaxation time were superior to SI-based indices.

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