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Abstract #4758

MRI-Based Stress Analyses of Abdominal Aortic Aneurysms With Resolved Intraluminal Thrombus Heterogeneity

Joseph R Leach1, Chengcheng Zhu1, David Saloner1, and Michael D Hope1

1Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, United States

Computational stress analyses of abdominal aortic aneurysms (AAA) are of great interest for individual aneurysm rupture risk assessment. The vast majority of patient-specific stress analyses are based on features seen at computed tomography, which is incapable of resolving material heterogeneity within intraluminal thrombus. Using T1-weighted black blood MRI, we imaged and explicitly modeled MRI-discerned intraluminal thrombus heterogeneity in multiple AAA stress analyses. Results demonstrate a limited effect of thrombus heterogeneity on the predicted vessel wall stresses, but suggest a possible role for MRI to inform thrombus material stiffness assignment in stress computations.

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