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Abstract #4767

Feasibility of EPI for cardiac diffusion at 7T

Elizabeth M Tunnicliffe1, Jesper L R Andersson2, Aaron T Hess1, and Matthew D Robson1

1Oxford Centre for Clinical Magnetic Resonance Research, University of Oxford, Oxford, United Kingdom, 2Oxford Centre for Functional MRI of the Brain, University of Oxford, Oxford, United Kingdom

Cardiac diffusion imaging promises new insights into myocardial microstructure and integrity, but is an SNR-starved technique. Imaging at 7T may enable fewer signal averages, but most cardiac diffusion implementations use an EPI readout, which suffers from spatial distortion at higher field strengths. In this work we demonstrate distortion-corrected, EPI-based, cardiac diffusion tensor imaging at 7T using images acquired with forward and reversed phase encoding directions. We find myocardial ADC and FA consistent with previously published 3T data and that, with this acquisition protocol, distortion correction does not lead to statistically significant changes in ADC and FA.

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