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Abstract #4766

Detection of early phase of deep vein thrombosis with diffusion-weighted magnetic resonance imaging.

Yasuyoshi Kuroiwa1,2, Atsushi Yamashita2, Toshihiro Gi2, Yuko Mizutani3, Taketoshi Asanuma3, Tosiaki Miyati4, Takuroh Imamura5, and Yujiro Asada2

1Department of Radiological Technology, Koga general hospital, Miyazaki, Japan, 2Department of Pathology, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan, 3Department of Radiology, Faculty of Veterinary Medicine, University of Miyazaki, Miyazaki, Japan, 4Faculty of Health Sciences, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan, 5Department of Internal Medicine, Koga General Hospital, Miyazaki, Japan

To detect and characterize deep vein thrombus (DVT), we performed diffusion weighted magnetic resonance imaging (MRI) in 8 patients and a rabbit model of DVT. All patients were detected DVT as high or mixed high and iso signal intensity on diffusion weighted MRI. The rabbit venous thrombi showed high signal intensity on diffusion weighted MRI at 4 hours, or mixed iso to high and low signal intensity at 1, 2, 3 weeks. The signal intensity was positively correlated with erythrocyte contents. Diffusion weighted MRI can detect DVT and high signal intensity on the sequence may reflect early phase of DVT.

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