Abstract #4801

Analyzation and Optimization of Simultaneous Non-Contrast Angiography and intraPlaque Hemorrhage (SNAP) Magnetic Resonance Angiography in Intracranial Vascular Imaging

Yuhui Xiong¹, Le He¹, Yu Ma², Xihai Zhao¹, Chun Yuan^1,3, and Hua Guo¹

¹Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China, ²Tsinghua University Yuquan Hospital, Beijing, China, ³Vascular Imaging Laboratory, Department of Radiology, University of Washington, Seattle, WA, United States

In this study, we used theoretical simulation and in-vivo scan validation to explore the relationship between intracranial SNAP-MRA signal and blood flow velocity to explain why the performance of SNAP-MRA may vary greatly between healthy people and patients with neurodegenerative diseases. We also found the way to re-optimize the scan parameters (TI and flip angle) to enhance the SNAP-MRA signal and acquire high quality intracranial SNAP-MRA.

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