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Abstract #4801

Analyzation and Optimization of Simultaneous Non-Contrast Angiography and intraPlaque Hemorrhage (SNAP) Magnetic Resonance Angiography in Intracranial Vascular Imaging

Yuhui Xiong1, Le He1, Yu Ma2, Xihai Zhao1, Chun Yuan1,3, and Hua Guo1

1Center for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China, 2Tsinghua University Yuquan Hospital, Beijing, China, 3Vascular Imaging Laboratory, Department of Radiology, University of Washington, Seattle, WA, United States

In this study, we used theoretical simulation and in-vivo scan validation to explore the relationship between intracranial SNAP-MRA signal and blood flow velocity to explain why the performance of SNAP-MRA may vary greatly between healthy people and patients with neurodegenerative diseases. We also found the way to re-optimize the scan parameters (TI and flip angle) to enhance the SNAP-MRA signal and acquire high quality intracranial SNAP-MRA.

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