Abstract #4802

3D high resolution Black Blood(BB) Multiple Echo(ME) T2* Imaging Technique for Quantitative Ferumoxytol Imaging on Delayed Scans

Seong-Eun Kim¹, J Scott Scott McNalley¹, Adam de Havenon ², Dennis L Parker¹, and Gerald S Treiman ³

¹UCAIR, Department of Radiology and Imaging Sciences, University of Utah, Salt Lake City, UT, United States, ²Department of Neurology, University of Utah, Salt Lake City, UT, United States, ³Department of Veterans Affairs, VASLCHCS, Salt Lake City, UT, United States

The purpose of this work was to develop a 3D BB ME T2* Imaging technique to to allow quantitative ferumoxytol imaging on delayed scans by measuring T2* in intracranial atherosclerotic plaque(ICAD). Post-gadoliniun enhancement in ICAD may be related to endothelial dysfunction or breakdown or secondary to plaque inflammation. Delayed ferumoxytol imaging allows intravascular clearance with retention in the macrophages present in vulnerable atherosclerotic plaque. We developed a 3D BB ME T2* imaging technique to allow quantitative ferumoxytol imaging on delayed scans by measuring T2* in ICAD.

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