Abstract #4804

Dynamic Susceptibility Contrast and Dynamic Contrast Enhanced Perfusion Performed in a Single Acquisition Using mDIXON Quant

Brian Johnson¹, Sandeep Ganji^2,3, and Ivan Dimitrov^2,4

¹Philips, Dallas, TX, United States, ²Philips Healthcare, Gainesville, FL, United States, ³Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX, United States, ⁴Advanced Imaging Research Center, University of Texas Southwestern Medical Center, DALLAS, TX, United States

This work investigates the use of mDIXON Quant as a perfusion technique to acquire dynamic susceptibility contrast (DSC) and dynamic contrast enhanced (DCE) scans in a single acquisition. The use of multi-echo mDIXON Quant for assessment of perfusion can be used to eliminate the need for split dosing and allows for acquiring DCE and DSC in a single acquisition. Elimination of a split contrast dose will remove contamination from changes in T1, T2, and T2*. This technique can potentially simplify the workflow for the DCE- based perfusion MRI imaging and reduce overall scan time.

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