Vulnerable atherosclerotic plaque in intracranial and extracranial carotid arteries and aortic arch is one of major causes of ischemic stroke. This study investigated the characteristics of atherosclerotic plaques in the craniocervical arteries and aortic arch and their relationships with stroke risk using 3D multicontrast MR vessel wall imaging. We found that high risk atherosclerotic plaques were most prevalent in intracranial arteries among three vascular beds. Combination of the maximum wall thickness in intracranial with extracranial carotid arteries might be a stronger predictor for cerebral acute ischemic lesions than that in each vascular bed alone.
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