We aim to investigate the longitudinal changes in the structural brain network of patients with acute subcortical ischemic infarct in the motor system, and the relation between motor recovery and network measures. Our results showed that the nodal degree of parahippocampus, amygdala, calcarine fissure, cuneus and fusiform gyrus increased with time after stroke, and that network topology measured at acute phase was associated with the recovery of motor function at 6 months after stroke. These findings suggested that network topology could potentially be a prognostic indicator of motor recovery for patients with acute subcortical ischemic infarct in the motor system.
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