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Abstract #4833

Predicting Hyperperfusion syndrome by measurement of leptomenigeal collateral and preoperative cerebral blood flow in patients with unilateral internal carotid artery stenosis

Yina Lan1, Jinhao Lyu1, Jianxun Qu2, Lin Ma1, and Xin Lou1

1Radiology and Imaging, Chinese People’s Liberation Army (PLA) General Hospital, Beijing, China, 2General Electric Healthcare, Shang hai, China

Hyperperfusion syndrome (HPS) is a rare but potentially fatal postoperative complication after revascularization, while preoperative predictor of HPS had not been fully established. We used pseudo continuous arterial spin labeling (pCASL) to investigate the correlation between the collateral flow proportion and the elevated cerebral blood flow (CBF) ratio relative to the preoperative CBF in patients with unilateral internal carotid artery (ICA) stenosis. A significant correlation was observed between the collateral flow proportion and the elevated CBF ratio . (r =0.588, P =0 .01). As an indication, HPS are likely to occur in patients with low preoperative CBF and good collateralization.

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