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Abstract #4838

Correlation between Intracranial Artery Atherosclerotic Disease and the Integrity of Circle of Willis in Symptomatic Patients: A 3D MR Vessel Wall Imaging Study.

Yilan Xu1, Dongye Li2,3, Zhuozhao Zheng1, Chun Yuan2,4, and Xihai Zhao2

1Department of Radiology, Beijing Tsinghua Changgung Hospital, Tsinghua University, Beijing, China, 2Center for Biomedical Imaging Research, Department of Biomedical Engineering, Tsinghua University School of Medicine, Beijing, China, 3Center for Brain Disorders Research, Capital Medical University and Beijing Institute for Brain Disorders, Beijing, China, 4Department of Radiology, University of Washington, Seattle, WA, United States

This study investigated the correlation between intracranial artery atherosclerotic disease and the integrity of communicating arteries in circle of Willis in symptomatic patients using MR imaging. We found that the intracranial artery stenosis was significantly associated with presence of anterior and posterior communicating arteries. Our findings suggest that the intracranial artery stenosis might be an independent indicator for the integrity of circle of Willis. Our data also suggest that, with the progression of intracranial artery stenosis, collateral circulation tends to be integrated from the anterior to posterior communicating arteries.

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