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Abstract #4839

Brain Perfusion and Structure Variation of Patients with Unilateral Middle Cerebral Artery Stenosis

Shuang Yan1, Tianyi Qian2, Mingli Li1, Li Zhang3, and Zhengyu Jin1

1Radiology, Peking Union Medical College Hospital, Peking Union Medical College, Beijing, China, 2Siemens Healthcare, MR Collaborations NE Asia, Beijing, China, 3Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China

To investigate the brain structure variation of patients with chronic unilateral middle cerebral artery (MCA) stenosis, a volume-based quantitative segmentation method was used to measure the morphological changes of brain structure. A correlation analysis was performed to find the relationship between the morphometry and cerebral blood perfusion. The results showed that the patients had atrophy in many brain regions within the MCA territory. And the perfusion status may have impact on the atrophy process.

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