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Abstract #4867

Single Acquisition Multiparametric MRI for Differentiation of Left Ventricular Scar Tissue Composition

Zahra Hosseini1,2, Junmin Liu1, Nikolaos Tzemos3, Raymond Yee3, and Maria Drangova1,4

1Robarts Research Institute, Western University, London, ON, Canada, 2Graduate Program in Biomedical Engineering, Western University, London, ON, Canada, 3Department of Medicine, Western University, London, ON, Canada, 4Biomedical Engineering, Western University, London, ON, Canada

Cardiac MRI plays a key role in identifying heart failure patients' response to cardiac resynchronization therapy. The identification of healthy myocardial regions for lead implantation is accomplished by means of late gadolinium enhancement MRI using exogenous contrast agents. Most MRI techniques that enable non-contrast cardiac tissue characterization are magnitude-based. MRI phase is an effective standalone source of information. However, most successful phase-based imaging is performed at lower field strength to alleviate field inhomogeneity-related artifacts. We present the application of a robust multiparametric magnitude- and phase-based myocardial mapping approach for scar tissue characterization at 3T.

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