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Abstract #4877

Clinical validation of the T1blood-based synthetic hematocrit used to calculate the ECV on 3T MRI in patients with type 2 diabetes mellitus and hypertrophic cardiomyopathy

Xiaoyue Zhou1, Yongning Shang2,3, Xiaochun Zhang2,3, and Jian Wang2,3

1Siemens Healthcare Ltd., Shanghai, China, 2Third Military Medical University, Chongqing, China, 3Southwest Hospital, Chongqing, China

Calculation of the extracellular volume fraction is based on a patient’s hematocrit (Hct), which can be obtained via a clinical blood test or can be estimated synthetically according its linear relationship with the native T1 of the blood. However, the reliability of the synthetic Hct needs to be studied further. We therefore assessed the clinical validation of the synthetic Hct compared with the Hct derived from a blood test in patients with type 2 diabetes mellitus and hypertrophic cardiomyopathy.

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