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Abstract #4896

Influence of respiration-induced B0 variations in CSF flow quantification

Kristina Peters1, René Bastkowski1, Kilian Weiss1,2, David Maintz1, and Daniel Giese1

1Institute of Diagnostic and Interventional Radiology, University Hospital Cologne, Cologne, Germany, 2Philips GmbH Healthcare, Hamburg, Germany

Susceptibility changes and resulting B0 changes during the respiratory cycle lead to phase variations in cerebrospinal fluid phase-contrast flow measurements and might be erroneously misinterpreted as physiological flow changes. These B0 changes were analysed by acquiring flow compensated and flow encoded real-time, single-shot EPI images. The respiration-induced phase variations in phase-contrast images were found to depend on the magnetic field strength, the delay between the flow compensated and flow encoded images and the depth and frequency of respiration. Thus, respiration-induced B0 variations need to be corrected prior to analysing true respiration-dependent cerebrospinal fluid flow measured by real-time phase-contrast MRI.

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