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Abstract #4905

Cardiac and Respiratory Self-Gated Motion-Corrected Free-Breathing Spiral Cine Imaging.

Ruixi Zhou1, Yang Yang2, Roshin Mathew3, and Michael Salerno4

1Biomedical Engineering, University of Virginia, Charlottesville, VA, United States, 2Medicine, Cardiovascular Division, University of Virginia, Charlottesville, VA, United States, 3Medicine, Cardiovascular Medicine, University of Virginia, Charlottesville, VA, United States, 4Medicine, Radiology and Medical Imaging, University of Virginia, Charlottesville, VA, United States

We developed a free-breathing continuous-acquisition respiratory and cardiac self-gated spiral cine pulse sequence. Data was acquired using a single spiral interleaf rotated by the golden-angle in time. The cardiac self-gating signal was extracted using principal component analysis on a gridded 8x8 central region of k-space for each spiral, and the respiratory motion is derived from rigid registration for each heartbeat. Images were reconstructed with motion compensated SPIRiT using 16 seconds (2000 spirals) or 8 seconds of data. Free-breathing self-gated spiral cine imaging demonstrated high image quality providing whole heart coverage with clinical spatial and temporal resolution in under 3 minutes.

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