Abstract #4904

Simultaneous T1 and T2 Mapping of the Carotid Artery with T2 and Inversion Recovery Prepared 3D Radial Imaging

Haikun Qi¹, Jie Sun², Huiyu Qiao¹, Rui Guo¹, Xihai Zhao¹, Niranjan Balu², Zechen Zhou³, Chun Yuan^1,2, and Huijun Chen¹

¹Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China, ²Department of Radiology, University of Washington, Seattle, WA, United States, ³Philips Research China, Shanghai, China

Multi-contrast MRI has been widely used for comprehensive characterization of atherosclerotic plaque. However, the qualitative nature and long scan time have limited its clinical application. In this study, a 3D high spatial resolution time-efficient technique, iGOAL-SNAP, is proposed, which generates different T1 and T2 contrasts in a single scan of 8min, enabling simultaneous T1 and T2 mapping. In addition, a rapid B1 correction method is presented in the fitting process. The accuracy and feasibility of iGOAL-SNAP was demonstrated using phantoms and in vivo studies.

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