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Abstract #4904

Simultaneous T1 and T2 Mapping of the Carotid Artery with T2 and Inversion Recovery Prepared 3D Radial Imaging

Haikun Qi1, Jie Sun2, Huiyu Qiao1, Rui Guo1, Xihai Zhao1, Niranjan Balu2, Zechen Zhou3, Chun Yuan1,2, and Huijun Chen1

1Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China, 2Department of Radiology, University of Washington, Seattle, WA, United States, 3Philips Research China, Shanghai, China

Multi-contrast MRI has been widely used for comprehensive characterization of atherosclerotic plaque. However, the qualitative nature and long scan time have limited its clinical application. In this study, a 3D high spatial resolution time-efficient technique, iGOAL-SNAP, is proposed, which generates different T1 and T2 contrasts in a single scan of 8min, enabling simultaneous T1 and T2 mapping. In addition, a rapid B1 correction method is presented in the fitting process. The accuracy and feasibility of iGOAL-SNAP was demonstrated using phantoms and in vivo studies.

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