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Abstract #4911

Simultaneous multislice spiral cine DENSE MRI

Changyu Sun1, Yang Yang2, Xiaoying Cai 1, Sophia Cui1, Daniel Auger1, Michael Salerno1,2,3, and Frederick H. Epstein1,3

1Biomedical Engineering, University of Virginia, Charlottesville, VA, United States, 2Medicine, University of Virginia, Charlottesville, VA, United States, 3Radiology, University of Virginia, Charlottesville, VA, United States

Spiral cine DENSE is an established method for imaging myocardial strain, however a relatively long acquisition time is a limitation. We developed a simultaneous multislice (SMS) method to accelerate spiral cine DENSE imaging. For SMS excitation we employed CAIPIRINHA phase modulation of the multiple slices. For the SMS reconstruction, we implemented a modified iterative conjugate gradient sensitivity encoding (CG-SENSE) method. Simulations and experiments in phantoms show that a 10-15% error occurs when imaging two slices simultaneously. Two-slice volunteer SMS images showed close agreement with separately-acquired single-slice images. SMS with CG-SENSE may be an effective means to accelerate spiral cine DENSE.

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