Abstract #4912

Effects of sex and age on CMR-derived left ventricular wall thickness and peak systolic wall stress in normal subjects

Xiaodan Zhao¹, Angela S Koh^1,2, Soo Kng Teo³, Sen Lin², Shuang Leng¹, Ris Low¹, Yi Su³, Ru San Tan^1,2, and Liang Zhong¹

¹National Heart Centre Singapore, Singapore, Singapore, ²Duke-NUS Medical School Singapore, Singapore, Singapore, ³Institute of High Performance Computing, A*STAR, Singapore, Singapore, Singapore

To investigate the left ventricular (LV) wall thickness, LV wall stress and their association with age and sex in a cohort of 210 healthy subjects (age: 19 to 87 years), endocardial and epicardial contour meshes from stacks of 2D short axis images were imported into our in-house software (CardioWerkz) for further analysis of 3D regional wall thickness and peak systolic wall stress (PSWS). Results indicated that mean LV wall thickness was smaller in females than males, and more positively correlated with age in female than male. Moreover, no significant difference for mean PSWS between females and males.

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