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Abstract #4916

INVESTIGATION OF CEREBRAL BLOOD FLOW PULSATILITY IN AGING PROCESS USING PHASE CONTRAST MAGNETIC RESONANCE IMAGING

Armelle LOKOSSOU1, Bader CHAARANI1, Souraya ELSANKARI1, Catherine GONDRY-JOUET2, and Olivier BALEDENT1

1Department of Medical Image Precessing, Amiens University Hospital, BioFlowImage Laboratory/Chimère, University of Picardie Jules Verne, Amiens, France, 2Department of Radiology, Amiens University Hospital, Amiens, France

No study already evaluated how arterial blood flow is transferred from extracranial to intracranial level and how venous outflow is transferred from intracranial sinuses to jugular veins. Healthy young and elderly volunteers were enrolled and underwent phase contrast magnetic resonance imaging to investigate intracranial and extracranial arterial and venous flows. In both groups, we found a significant decrease of arterial and venous flows pulsatilities inside the cranium. However, the intracranial and extracranial cerebral blood flow pulsatilities increased significantly with age.

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