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Abstract #4940

Within-Subject Characterization of Sports Concussion with Serial Diffusion MRI and Spherical Mean Technique

Matthew Budde1, L. Tugan Muftuler1, Andrew Nencka2, Kevin Koch2, Yang Wang2, Timothy Meier1, and Michael McCrea1

1Neurosurgery, Medical College of Wisconsin, Milwaukee, WI, United States, 2Radiology, Medical College of Wisconsin, Milwaukee, WI, United States

Diffusion tensor imaging is a promising biomarker of mild Traumatic Brain Injury and concussion, but it has not been refined sufficiently for diagnosis in individual subjects. In this study, we demonstrate that spherical mean technique (SMT) diffusion MRI can detect post-concussion changes in single subjects over the acute recovery period.

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