Recently, Ware and colleagues1 showed that FA-derived damage assessment in WM regions can accurately classify subjects with processing speed impairment in moderate to severe diffuse TBI at 3 months post-injury. Using a subset of the same cohort who completed follow-up DTI scans at 6 and 12 months post-injury, the goals of this study were 1) to investigate if regional FA remains associated with processing speed in a dataset including all time points and 2) to conduct an exploratory analysis to identify a subset of regions that can best explain such association. Four regions were identified that explained most variance in processing speed.
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