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Abstract #4948

Using fMRI to assess cerebrovascular reactivity after acute concussion

Nathan W Churchill1, Michael Hutchison2, Simon Graham3, and Tom Schweizer4

1Neuroscience Research Program, St. Michael's Hospital, Toronto, ON, Canada, 2University of Toronto, Toronto, ON, Canada, 3Sunnybrook Hospital, Toronto, ON, Canada, 4St. Michael's Hospital, Toronto, ON, Canada

Cerebrovascular reactivity (CVR) is an important biomarker of concussion, as brain activity and blood flow regulation are often impaired after brain injury. This study examines an fMRI breath hold paradigm as a probe of CVR in concussed athletes, showing significant variations with days post-injury.

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