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Abstract #4965

Towards the Macaque Connectome: 24-Channel 3T Multi-Array Coil, MR Sequences, and HCP-style Preprocessing

Joonas Autio1, Takayuki Ose1, Masahiro Ohno1, Yoshihiko Kawabata2, Yuta Urushibata3, Kantaro Nishigori1, Masataka Yamaguchi1, Yuki Hori1, Atsushi Yoshida1, Katsutoshi Murata3, Matthew Glasser4,5, and Takuya Hayashi1

1Center for Life Science Technologies, RIKEN, Kobe, Japan, 2Takashima Seisakusho Co., Ltd, Tokyo, Japan, 3Siemens Healthcare Japan, Tokyo, Japan, 4Department of Neuroscience, Washington University, St. Louis, MO, United States, 5St. Luke's hospital, St. Louis, MO, United States

Macaque monkeys are an important neuroscientific model for understanding cortical organization of primates, yet non-human primate MRI applications have lagged behind those developed for humans. To address this issue, we developed a 24-channel receive coil for macaque brain imaging and adapted the Human Connectome Project (HCP)’s image acquisition protocols matched to monkey’s neuroanatomical resolution. By adapting HCP’s preprocessing methods for the macaque, we demonstrate that the resulting HCP-style monkey MRI data show great promise for multi-modal analyses of cortical architecture and connectivity, which have previously only been possible in humans.

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